BDBM372326 N-[1-(5-Fluoropyrimidin-2-yl)azetidin-3-yl]-3,4-dimethyl-pyrimido[4′,5′:4,5]furo[2,3-c]pyridazin-8-amine ::US10239887, Cpd. No. 63

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ncc4c([C@H]5[C@@H]6CNC[C@@H]65)cn(C)c4c3F)c12

InChI Key InChIKey=ZAMOBUARVGIEQA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372326   

TargetGTPase NRas [G12D](Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 372326BDBM372326(US20260022118, Example 2)
Affinity DataKd:  52.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent