BDBM373161 US9896452, Example 23::rac-(5-(4-fluorophenyl)-2-methylthiazol-4-yl)((2S,3R)-3-methyl-2-(((6-methylpyridin-2-yl)amino)methyl)piperidin-1-yl)methanone

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ncc4c(c(C)cn4C4CC5CCC4CN5)c3F)c12

InChI Key InChIKey=JDJXIYFKTPJOKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373161   

TargetGTPase NRas [G12D](Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 373161BDBM373161(US20260022118, Example 39)
Affinity DataKd:  435nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent