BDBM373181 US9896452, Example 41::rac-N-((1-(biphenylcarbonyl)-5-(dimethylamino)piperidin-2-yl)methyl)quinoline-8-carboxamide

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3nc(OC4CC(F)(F)C4)c4c([C@H]5[C@@H]6CNC[C@@H]65)nn(C5CC5)c4c3F)c12

InChI Key InChIKey=PQHANPYFHWQTGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373181   

TargetGTPase NRas [G12D](Human)
University of Texas System

US Patent
LigandChemical structure of BindingDB Monomer ID 373181BDBM373181(US20260022118, Example 68)
Affinity DataKd:  566nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent