BDBM42292 (R)-2-(3-((2-fluoroethoxy)methyl)-4-(pyrimidin-4-yl)piperazin-1-yl)-5-((2-(1-methyl-1H-pyrazol-4-yl)pyrimidin-5-yl)ethynyl)pyrimidine::WO2024186584, Example 53

SMILES FCCOC[C@H]1CN(CCN1C1=NC=NC=C1)C1=NC=C(C=N1)C#CC=1C=NC(=NC1)C=1C=NN(C1)C

InChI Key InChIKey=TVPPOVOXHDIISQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 42292   

TargetAlpha-synuclein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42292BDBM42292((R)-2-(3-((2-fluoroethoxy)methyl)-4-(pyrimidin-4-y...)
Affinity DataKi:  0.320nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent