BDBM43856 4-ethoxy-N-[(6-fluoro-1,1-diketo-2,3-dihydrothiochromen-4-ylidene)amino]benzenesulfonamide::4-ethoxy-N-[(6-fluoro-1,1-dioxo-2,3-dihydro-1-benzothiopyran-4-ylidene)amino]benzenesulfonamide::4-ethoxy-N-[(6-fluoro-1,1-dioxo-2,3-dihydrothiochromen-4-ylidene)amino]benzenesulfonamide::4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxidanylidene)-2,3-dihydrothiochromen-4-ylidene]amino]benzenesulfonamide::MLS000761277::Non peptidic, 3::SMR000369580::cid_3596078

SMILES CCOc1ccc(cc1)S(=O)(=O)NN=C1CCS(=O)(=O)c2ccc(F)cc12

InChI Key InChIKey=AIOGLQGMWXKIAI-UHFFFAOYSA-N

Data  28 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 43856   

TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  20nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  30nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  30nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  30nM IC50: 30nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  30nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  30nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  40nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  40nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  50nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  50nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  70nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  70nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  70nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  90nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  90nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  100nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  110nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  150nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  220nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  240nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  460nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  460nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  540nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataIC50: 5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataIC50: 5.30E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2011
Entry Details
PCBioAssay
TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Nippon Roche Research Center

LigandPNGBDBM43856(cid_3596078 | 4-ethoxy-N-[[6-fluoranyl-1,1-bis(oxi...)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed