BDBM48867 (5Z)-2,6-diketo-4-methyl-5-[[5-(4-methyl-2-nitro-phenyl)-2-furyl]methylene]nicotinonitrile::(5Z)-2-hydroxy-4-methyl-5-{[5-(4-methyl-2-nitrophenyl)-2-furyl]methylene}-6-oxo-5,6-dihydropyridine-3-carbonitrile::(5Z)-4-methyl-5-[[5-(4-methyl-2-nitro-phenyl)furan-2-yl]methylidene]-2,6-bis(oxidanylidene)pyridine-3-carbonitrile::(5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)-2-furanyl]methylidene]-2,6-dioxo-3-pyridinecarbonitrile::(5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-2-yl]methylidene]-2,6-dioxopyridine-3-carbonitrile::MLS000724113::SMR000305708::cid_5884223

SMILES Cc1ccc(-c2ccc([CH+]c3c(C)[c-](C#N)c(=O)[nH]c3=O)o2)c(c1)[N+]([O-])=O

InChI Key InChIKey=NNYFCPFQGDTGSR-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 48867   

TargetHuntingtin(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 784nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 2.68E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetSUMO-conjugating enzyme UBC9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 5.46E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 1.31E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataEC50:  2.18E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetSUMO-activating enzyme subunit 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 3.56E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataEC50:  3.64E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
LigandPNGBDBM48867((5Z)-4-methyl-5-[[5-(4-methyl-2-nitrophenyl)furan-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay