BDBM50010947 6-Pyridin-3-yl-6-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-hexanoic acid::CHEMBL91799

SMILES Cc1c(C)c(O)c(C(=CCCCC(O)=O)c2cccnc2)c(C)c1O

InChI Key InChIKey=ILHHWMSWSYYXCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010947   

TargetThromboxane-A synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010947(CHEMBL91799 | 6-Pyridin-3-yl-6-(2,4,5-trimethyl-3,...)
Affinity DataIC50: 89nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010947(CHEMBL91799 | 6-Pyridin-3-yl-6-(2,4,5-trimethyl-3,...)
Affinity DataIC50: 6.00E+4nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed