BDBM50010952 2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl-[1,4]benzoquinone::CHEMBL93678

SMILES Cc1c(C)c(O)c(C(=CCCCCO)c2cccnc2)c(C)c1O

InChI Key InChIKey=KNAOMBWWMLPNNT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010952   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010952(CHEMBL93678 | 2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3...)
Affinity DataIC50: 100nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010952(CHEMBL93678 | 2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3...)
Affinity DataIC50: 820nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010952(CHEMBL93678 | 2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3...)
Affinity DataIC50: 900nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed