BDBM50010954 2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benzoquinone::CHEMBL89938

SMILES Cc1c(C)c(O)c(C(=C)c2cccnc2)c(C)c1O

InChI Key InChIKey=IQZRJKREGNVSRE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010954   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010954(CHEMBL89938 | 2,3,5-Trimethyl-6-(1-pyridin-3-yl-et...)
Affinity DataIC50: 720nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010954(CHEMBL89938 | 2,3,5-Trimethyl-6-(1-pyridin-3-yl-et...)
Affinity DataIC50: 720nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010954(CHEMBL89938 | 2,3,5-Trimethyl-6-(1-pyridin-3-yl-et...)
Affinity DataIC50: 9.50E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed