BDBM50010959 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-propionic acid::CHEMBL327426

SMILES Cc1c(O)c(C=CC(O)=O)c(C)c(O)c1Cc1cccnc1

InChI Key InChIKey=UBJGBZSOBVYMJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010959   

TargetThromboxane-A synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010959(CHEMBL327426 | 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin...)
Affinity DataIC50: 970nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010959(CHEMBL327426 | 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin...)
Affinity DataIC50: 5.00E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed