BDBM50011561 CHEMBL3262580::US9592235, Example 174::US9855269, Compound 18

SMILES Nc1ncnc2ccc(cc12)-c1cccc(F)c1

InChI Key InChIKey=MXJWENZEPDIULQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011561   

LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50: 45.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50: 45.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50: 58nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed