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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 4' and Ligand = 'BDBM50011561'
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50:  45.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50:  45.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50:  58nMAssay Description:Inhibition of MAP4K4 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed