BDBM50012133 CHEMBL3263699

SMILES CC(C)CN(Cc1ccc(s1)-c1ccc(NS(C)(=O)=O)cc1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=OJSRHOUBAZHNFM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012133   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50012133(CHEMBL3263699)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50012133(CHEMBL3263699)
Affinity DataIC50: 71nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from human RORc-LBD after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50012133(CHEMBL3263699)
Affinity DataEC50:  150nMAssay Description:Inverse agonist activity at an N-terminal 6xHis-GST-tag human RORc-LBD assessed as inhibition of recruitment of the SRC1 co-activator peptide after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed