BDBM50014857 2,2,2-Trifluoro-N-(3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::CHEMBL346431

SMILES COc1c(O)cc2CC[C@H](NC(=O)C(F)(F)F)c3cc(=O)c(SC)ccc3-c2c1OC

InChI Key InChIKey=GNDJEEOMNARHHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014857   

TargetTubulin beta-2B chain(Bovine)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014857(CHEMBL346431 | 2,2,2-Trifluoro-N-(3-hydroxy-1,2-di...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory effect on the polymerization of purified bovine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed