BDBM50024406 5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile::CHEMBL8068

SMILES Cc1[nH]c(=O)c(cc1-c1ccc(cc1)-n1ccnc1)C#N

InChI Key InChIKey=KWFAYMFYKQGTML-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50024406   

LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 3 from guinea pig, range 1.68-2.03More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 1 from guinea pig, range 15-33More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 2 from guinea pig, range 27-41More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50: 3.88E+4nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 1 from guinea pig, range 34-43More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 2 from guinea pig, range 37-49More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed