BDBM50026553 (+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::(+/-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::(-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol (DP-5,6-ADTN)::CHEMBL11845

SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O

InChI Key InChIKey=JQHSYAQISCFWOK-UHFFFAOYSA-N

Data  3 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50026553   

TargetD(2) dopamine receptor(Human)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataEC50:  0.700nMAssay Description:Tested for intrinsic activity towards Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2018
Entry Details Article
PubMed
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptors in striata of female wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2018
Entry Details Article
PubMed
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataIC50: 80nMAssay Description:50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi:  170nMAssay Description:In vitro binding affinity towards Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University Center For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataKi: >217nMAssay Description:Tested for affinity against cloned mammalian dopamine autoreceptor (DA) D2 receptors expressed in CHO-K1 cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50026553((-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed