BDBM50037324 CHEMBL109852::{2-Oxo-6-phenethyl-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,2-dihydro-pyridin-3-yl}-carbamic acid benzyl ester

SMILES CC(C)C(NC(=O)Cn1c(CCc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F

InChI Key InChIKey=VRFKDHIVWIZNIG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037324   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037324({2-Oxo-6-phenethyl-1-[(3,3,3-trifluoro-1-isopropyl...)
Affinity DataKi:  79nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037324({2-Oxo-6-phenethyl-1-[(3,3,3-trifluoro-1-isopropyl...)
Affinity DataKi:  9.60E+3nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed