BDBM50037853 CHEMBL334305::{(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-8-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetic acid tert-butyl ester

SMILES Cc1ccc2[C@H](C[C@@H](NC(=O)Nc3cccc(Cl)c3)C(=O)N(CC(=O)OC(C)(C)C)c2c1)c1ccccc1

InChI Key InChIKey=JJAYAAFBSRHMID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037853   

TargetGastrin/cholecystokinin type B receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037853({(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-8-methyl-2...)
Affinity DataIC50: 2.20nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037853({(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-8-methyl-2...)
Affinity DataIC50: 34nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed