BDBM50037853 CHEMBL334305::{(3R,5R)-3-[3-(3-Chloro-phenyl)-ureido]-8-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetic acid tert-butyl ester

SMILES Cc1ccc2[C@H](C[C@@H](NC(=O)Nc3cccc(Cl)c3)C(=O)N(CC(=O)OC(C)(C)C)c2c1)c1ccccc1

InChI Key InChIKey=JJAYAAFBSRHMID-JWQCQUIFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037853   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037853(CHEMBL334305 | {(3R,5R)-3-[3-(3-Chloro-phenyl)-ure...)
Affinity DataIC50:  2.20nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]-BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037853(CHEMBL334305 | {(3R,5R)-3-[3-(3-Chloro-phenyl)-ure...)
Affinity DataIC50:  34nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]-BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed