BDBM50044247 CHEMBL3314036::US9216988, 159

SMILES CC(C)CN(Cc1ccc(OC2CCN(CC2)S(C)(=O)=O)cc1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=SYYAUMCMYDORDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044247   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044247(US9216988, 159 | CHEMBL3314036)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044247(US9216988, 159 | CHEMBL3314036)
Affinity DataIC50: 6nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent