BDBM50044247 CHEMBL3314036::US9216988, 159

SMILES CC(C)CN(Cc1ccc(OC2CCN(CC2)S(C)(=O)=O)cc1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=SYYAUMCMYDORDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044247   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50044247(CHEMBL3314036 | US9216988, 159)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50044247(CHEMBL3314036 | US9216988, 159)
Affinity DataIC50:  6nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...More data for this Ligand-Target Pair
In DepthDetails US Patent