BDBM50045481 (3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine::CHEMBL291963

SMILES N(c1cccc(c1)-n1ccnc1)c1nccc(n1)-c1cccnc1

InChI Key InChIKey=IDWXVEDTQPGXCG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50045481   

TargetProtein kinase C alpha type(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
The First People'S Hospital of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProtein kinase C delta type(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of protein kinase C delta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article