BDBM50068542 CHEMBL3400826

SMILES Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1cn(C)c(=O)c(Nc2ccc(C(=O)NCCCNC(=S)Nc3ccc(-c4c5ccc(=O)cc-5oc5cc(O)ccc45)c(C(=O)O)c3)cc2)n1

InChI Key InChIKey=JPJLPHFCQVSFAD-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50068542   

TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068542BDBM50068542(CHEMBL3400826)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of biotinylated and unactivated BTK (unknown origin) using FITC-labeled Srctide peptide substrate and ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068542BDBM50068542(CHEMBL3400826)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to biotinylated and unactivated BTK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068542BDBM50068542(CHEMBL3400826)
Affinity DataIC50: 208nMAssay Description:Inhibition of biotinylated and activated BTK (unknown origin) using FITC-labeled Srctide peptide substrate and ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed