BDBM50075646 5-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethylamino]phenyl}-5-(3-pyridyl)-(E)-4-pentenoic acid::CHEMBL21072

SMILES CC(C)(C)NC(Nc1cccc(c1)C(=CCCC(O)=O)c1cccnc1)=NC#N

InChI Key InChIKey=PVQYCYOIOKLQMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075646   

TargetThromboxane-A synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075646(5-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethy...)
Affinity DataIC50:  400nMAssay Description:In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075646(5-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethy...)
Affinity DataIC50:  81nMAssay Description:In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed