BDBM50090494 (R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-6-one O-methyl-oxime::CHEMBL298420

SMILES CO\N=C1\CN2CC1[C@@H](CC2)c1ccc(Cl)cc1

InChI Key InChIKey=UXYPLFVCIANMBF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090494   

TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090494((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  232nMAssay Description:Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090494((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  304nMAssay Description:Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090494((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi:  434nMAssay Description:Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50090494((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed