BDBM50093082 CHEMBL3586573
SMILES CCN1C(=O)CNc2ncc(nc12)-c1ccc(nc1C)-c1nc[nH]n1
InChI Key InChIKey=GMYLVKUGJMYTFB-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50093082
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human cFMSMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human DNA PKMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair