BDBM50093082 CHEMBL3586573

SMILES CCN1C(=O)CNc2ncc(nc12)-c1ccc(nc1C)-c1nc[nH]n1

InChI Key InChIKey=GMYLVKUGJMYTFB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50093082   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  21nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human cFMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  15nMAssay Description:Inhibition of human DNA PKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  850nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  13nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  630nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFKBP12A/mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  23nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATM (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50:  21nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093082(CHEMBL3586573)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed