BDBM50111605 3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-indol-2-one::CHEMBL47173

SMILES O=C1Nc2ccccc2\C1=C\c1ccc(s1)-c1cccs1

InChI Key InChIKey=FXSZWRDLPDUWGV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50111605   

TargetVascular endothelial growth factor receptor 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human VEGFR2 using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human EGFR using peptide as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111605(3-[2,2']Bithiophenyl-5-ylmethylene-1,3-dihydro-ind...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed