BDBM50125821 4-Oxo-4-phenyl-but-2-enoic acid::4-oxo-4-phenylbut-2-enoic acid::CHEMBL16365

SMILES OC(=O)\C=C\C(=O)c1ccccc1

InChI Key InChIKey=PLPDHGOODMBBGN-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125821   

TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataEC50: >2.50E+5nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of recombinant ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells using LC3-GST as substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed