BDBM50125821 4-Oxo-4-phenyl-but-2-enoic acid::4-oxo-4-phenylbut-2-enoic acid::CHEMBL16365

SMILES OC(=O)\C=C\C(=O)c1ccccc1

InChI Key InChIKey=PLPDHGOODMBBGN-VOTSOKGWSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125821   

TargetPolymerase acidic protein(Hepatitis C virus)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataIC50:  5.80E+5nMAssay Description:Inhibition of recombinant ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells using LC3-GST as substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of cap 1 ALMV primed Influenza transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50125821(4-Oxo-4-phenyl-but-2-enoic acid | 4-oxo-4-phenylbu...)
Affinity DataEC50: >2.50E+5nMAssay Description:Plaque growth inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed