BDBM50132951 8-(2,4-dichlorophenyl)-2-methyl-N,N-dipropylquinolin-4-amine::CHEMBL432800::[8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-dipropyl-amine

SMILES CCCN(CCC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=SUYDJIHTAHBJRR-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132951   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50132951([8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-d...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]sauvagine from CRF1 receptor expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50132951([8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-d...)
Affinity DataKi:  0.900nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50132951([8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-d...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity towards cloned human CRF1 receptor expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurogen

Curated by ChEMBL
LigandPNGBDBM50132951([8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-d...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed