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Found 4 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50132951'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132951(8-(2,4-dichlorophenyl)-2-methyl-N,N-dipropylquinol...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity towards cloned human CRF1 receptor expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132951(8-(2,4-dichlorophenyl)-2-methyl-N,N-dipropylquinol...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]sauvagine from CRF1 receptor expressed in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132951(8-(2,4-dichlorophenyl)-2-methyl-N,N-dipropylquinol...)
Affinity DataKi:  0.900nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132951(8-(2,4-dichlorophenyl)-2-methyl-N,N-dipropylquinol...)
Affinity DataIC50:  17nMAssay Description:Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed