BDBM50151534 5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiazol-(2Z)-ylideneamino]-2-hydroxy-benzoic acid::CHEMBL184017
SMILES Cn1nc(s\c1=N/c1ccc(O)c(c1)C(O)=O)-c1ccc(Cl)cc1
InChI Key InChIKey=RZUPSYPYOYBGEM-VLGSPTGOSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50151534
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of human Phosphodiesterase 1 purified from THP-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of human Phosphodiesterase 5 purified from MCF-7 cellsMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of human Phosphodiesterase 3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.05E+3nMAssay Description:Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair