BDBM50170480 6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyridine-2-carboxylic acid (4-hydroxycarbamoylmethyl-thiazol-2-yl)-amide::CHEMBL366118

SMILES CCc1cc(C(C)=O)c(O)cc1OCc1cccc(n1)C(=O)Nc1nc(CC(=O)NO)cs1

InChI Key InChIKey=ZABQHWUKKILDGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170480   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50: 87nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed