BDBM50179073 (4R,9aR)-6-Cyclopropylmethoxymethyl-4-methyl-1,2,3,4,9,9a-hexahydro-2,4a,5-triaza-fluorene::CHEMBL203013
SMILES C[C@@H]1CNC[C@H]2Cc3ccc(COCC4CC4)nc3N12
InChI Key InChIKey=LJRLAJVWAFFRLV-IAQYHMDHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50179073
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >360nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: >720nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >720nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >720nMAssay Description:Binding affinity to D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >720nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: >720nMAssay Description:Binding affinity to 5HT5A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to NA transporterMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT transporterMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to mu type opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to beta1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to DA transporterMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Efficacy against human recombinant 5HT2C receptor induced intracellular calcium mobilization in CHO cells by FLIPRMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Efficacy against human recombinant 5HT2B receptor induced intracellular calcium mobilization in CHO cells by FLIPRMore data for this Ligand-Target Pair