BDBM50181315 4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)quinolin-2(1H)-one::CHEMBL204524

SMILES CN1CCN(c2ccc3[nH]c(-c4c(N)c5ccccc5[nH]c4=O)nc3n2)CC1

InChI Key InChIKey=ARXCFPVKEORMCL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181315   

TargetFibroblast growth factor receptor 1(Human)
Chiron

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50181315BDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181315BDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181315BDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181315BDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed