BDBM50181315 4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)quinolin-2(1H)-one::CHEMBL204524

SMILES CN1CCN(CC1)c1ccc2[nH]c(nc2n1)-c1c(N)c2ccccc2[nH]c1=O

InChI Key InChIKey=ARXCFPVKEORMCL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181315   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed