BDBM50186697 CHEMBL381735::benzyl (2S,3S)-3-methyl-1-((S)-1-((S)-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopropan-2-ylamino)-1,5-dioxo-5-(tert-pentylamino)pentan-2-ylamino)-1-oxopentan-2-ylcarbamate

SMILES CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)NC(C)(C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C=CS(C)(=O)=O

InChI Key InChIKey=XUMGNVHLIGZROX-DICHZVEKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186697   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186697(CHEMBL381735 | benzyl (2S,3S)-3-methyl-1-((S)-1-((...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186697(CHEMBL381735 | benzyl (2S,3S)-3-methyl-1-((S)-1-((...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186697(CHEMBL381735 | benzyl (2S,3S)-3-methyl-1-((S)-1-((...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed