BDBM50186702 Ac-hPhe-Leu-Phe-LeuVSMe::CHEMBL379669

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCc1ccccc1)NC(C)=O)\C=C\S(C)(=O)=O

InChI Key InChIKey=UIUWSHIRBDIYGM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186702   

TargetProteasome subunit beta type-5(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186702(Ac-hPhe-Leu-Phe-LeuVSMe | CHEMBL379669)
Affinity DataIC50: 35nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186702(Ac-hPhe-Leu-Phe-LeuVSMe | CHEMBL379669)
Affinity DataIC50: 150nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186702(Ac-hPhe-Leu-Phe-LeuVSMe | CHEMBL379669)
Affinity DataIC50: 850nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186702(Ac-hPhe-Leu-Phe-LeuVSMe | CHEMBL379669)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186702(Ac-hPhe-Leu-Phe-LeuVSMe | CHEMBL379669)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed