BDBM50186717 CHEMBL446443::Cbz-Ile-hPhe-Ala-LeuVSMe

SMILES CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C=CS(C)(=O)=O

InChI Key InChIKey=BZKLWACICJITOJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186717   

TargetProteasome subunit beta type-5(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186717(Cbz-Ile-hPhe-Ala-LeuVSMe | CHEMBL446443)
Affinity DataIC50: 27nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186717(Cbz-Ile-hPhe-Ala-LeuVSMe | CHEMBL446443)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186717(Cbz-Ile-hPhe-Ala-LeuVSMe | CHEMBL446443)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186717(Cbz-Ile-hPhe-Ala-LeuVSMe | CHEMBL446443)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50186717(Cbz-Ile-hPhe-Ala-LeuVSMe | CHEMBL446443)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed