BDBM50192681 CHEMBL218246::N-(5-cyanocyclooctyl)-2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanamide

SMILES CC(C)(N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)NC1CCCC(CCC1)C#N

InChI Key InChIKey=DJTWBQCPSRQQDF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50192681   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192681(N-(5-cyanocyclooctyl)-2-methyl-2-(4-(5-(trifluorom...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192681(N-(5-cyanocyclooctyl)-2-methyl-2-(4-(5-(trifluorom...)
Affinity DataIC50: 219nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192681(N-(5-cyanocyclooctyl)-2-methyl-2-(4-(5-(trifluorom...)
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192681(N-(5-cyanocyclooctyl)-2-methyl-2-(4-(5-(trifluorom...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192681(N-(5-cyanocyclooctyl)-2-methyl-2-(4-(5-(trifluorom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed