BDBM50195289 1-piperidin-1-yl-cyclopropanecarboxylic acid (5-hydroxy-adamantan-2-yl)-amide::CHEMBL220102
SMILES O[C@@]12C[C@H]3CC(C1)[C@H](NC(=O)C1(CC1)N1CCCCC1)C(C3)C2
InChI Key InChIKey=CEZQNMXBDYZVET-NIYRFRDPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50195289
Affinity DataKi: 2nMAssay Description:Inhibition of human truncated 11beta-HSD1 assessed as inhibition of radiolabeled cortisone to cortisol conversion by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of mouse truncated 11beta-HSD1 assessed as inhibition of radiolabeled cortisone to cortisol conversion by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of cortisol formation by fluorescent polarization immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human 11beta-HSD2 assessed as cortisol disappearance by SPAMore data for this Ligand-Target Pair