BDBM50197402 2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-propionamide::CHEMBL392932

SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)S(N)(=O)=O

InChI Key

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197402   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197402(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Affinity DataKi:  5nMAssay Description:Inhibition of human HSD1 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197402(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse HSD1 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197402(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human HSD1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197402(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human HSD2 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197402(2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adama...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse HSD2 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed