BDBM50243294 CHEMBL4094513
SMILES CN(CCN)Cc1ccccc1Sc1ccccc1Cl
InChI Key InChIKey=XCZUYGFLWBJNCB-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50243294
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PRMT8 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PRMT6 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of PRMT4 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1(Rattus norvegicus)
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) incubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1(Rattus norvegicus)
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT5 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Zhejiang Sci-Tech University
Curated by ChEMBL
Zhejiang Sci-Tech University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of PRMT3 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair