BDBM50243294 CHEMBL4094513

SMILES CN(CCN)Cc1ccccc1Sc1ccccc1Cl

InChI Key InChIKey=XCZUYGFLWBJNCB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50243294   

TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of PRMT8 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of PRMT6 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50:  63nMAssay Description:Inhibition of PRMT4 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Rattus norvegicus)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) incubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Rattus norvegicus)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of rat His-tagged PRMT1 (11 to 353 residues) expressed in Escherichia coli BL21(DE3) using biotinylated H4 peptide (1 to 21 residues) as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PRMT5 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50243294(CHEMBL4094513)
Affinity DataIC50:  22nMAssay Description:Inhibition of PRMT3 (unknown origin) incubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLisa methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed