BDBM50243632 (S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylbenzamide::CHEMBL469698

SMILES C[C@](O)(c1ccc(cc1)C(=O)N(C1CC1)C1CCCCC1)C(F)(F)F

InChI Key InChIKey=MMIDZOVIJQHNLX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243632   

LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human cloned 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50243632((S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 11beta-HSD2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed