BDBM50252478 2-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)phenoxy]-2-methylpropanoic acid::CHEMBL492433

SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1cccc(OC(C)(C)C(O)=O)c1)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=OHGJDYIYXOTBRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252478   

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252478BDBM50252478(2-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]...)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat 11betaHSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50252478BDBM50252478(2-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]...)
Affinity DataIC50: 130nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed