BDBM50252478 2-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)phenoxy]-2-methylpropanoic acid::CHEMBL492433
SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1cccc(OC(C)(C)C(O)=O)c1)c1ccc(F)cc1C(F)(F)F
InChI Key InChIKey=OHGJDYIYXOTBRB-CQSZACIVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50252478
Affinity DataIC50: 300nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of rat 11betaHSD1More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair