BDBM50258646 CHEMBL468935::N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctanediamide

SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCCC(=O)NO)n1

InChI Key InChIKey=DRRQFLRBTKPRMM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258646   

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258646(N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctan...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258646(N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctan...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258646(N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctan...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258646(N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctan...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed