BDBM50258646 CHEMBL468935::N1-(4-(3-aminophenyl)thiazol-2-yl)-N8-hydroxyoctanediamide

SMILES Nc1cccc(c1)-c1csc(NC(=O)CCCCCCC(=O)NO)n1

InChI Key InChIKey=DRRQFLRBTKPRMM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258646   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258646(CHEMBL468935 | N1-(4-(3-aminophenyl)thiazol-2-yl)-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258646(CHEMBL468935 | N1-(4-(3-aminophenyl)thiazol-2-yl)-...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258646(CHEMBL468935 | N1-(4-(3-aminophenyl)thiazol-2-yl)-...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258646(CHEMBL468935 | N1-(4-(3-aminophenyl)thiazol-2-yl)-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed